Safe T21 Advance (Advanced Edition) is designed for parents seeking the most detailed information regarding fetal health, providing "whole-genome" level screening. This advanced version not only examines all 23 pairs of chromosomes but also comprehensively covers over 126 microdeletion and microduplication syndromes (DNA segments ≥3Mb). Since microdeletions occur in approximately 1 in 100 pregnancies and are independent of maternal age, the advanced screening effectively mitigates the risks that the standard version might miss. Bless GD Twin (Twin Edition) is a non-invasive prenatal screening technology specifically designed for twin pregnancies, focusing on detecting single-gene diseases (SGDs) caused by specific point mutations or small fragment deletions within genes. It screens for 66 single-gene diseases across 34 genes, effectively identifying de novo (new) genetic mutations that could lead to intellectual disability, developmental delays, and physical structural abnormalities, including dwarfism and osteogenesis imperfecta (brittle bone disease).